Francis D D, Meaney M J
Developmental Neuroendocrinology Laboratory Douglas Hospital Research Center Departments of Psychiatry and Neurology & Neurosurgery 6875 Boul LaSalle McGill University Montréal Canada H4H 1R3.
Curr Opin Neurobiol. 1999 Feb;9(1):128-34. doi: 10.1016/s0959-4388(99)80016-6.
Studies dating from the 1950s have documented the impact of early life events on the development of behavioral and endocrine responses to stress. Recent findings suggest that these effects are mediated through changes in mother-offspring interactions and have identified central corticotropin-releasing factor systems as a critical target for the effects of variations in maternal care.
可追溯到20世纪50年代的研究记录了早期生活事件对压力的行为和内分泌反应发展的影响。最近的研究结果表明,这些影响是通过母婴互动的变化介导的,并确定中枢促肾上腺皮质激素释放因子系统是母婴护理变化影响的关键靶点。