Bonneux L, Barendregt J J, van der Maas P J
Department of Public Health, Erasmus University Rotterdam, The Netherlands.
Am J Public Health. 1999 Mar;89(3):379-82. doi: 10.2105/ajph.89.3.379.
This study quantified the consequences for prevalence of increased survival of coronary heart disease (CHD) in the Netherlands from 1980 to 1993.
A multistage life table fitted observed mortality and registration rates from the nationwide hospital register. The outcome was prevalence by age, sex, period, and disease state.
The prevalence of CHD from 1980 to 1993 was 4.4% (men, aged 25 to 84 years) and 1.4% (women, aged 25 to 84 years). Between 1980-1983 and 1990-1993, the incidence changed little, but age-adjusted prevalence increased by 19% (men) and 59% (women).
Sharply decreasing mortality but near-constant attack rates of CHD caused distinct increases in prevalence, particularly among the elderly.
本研究对1980年至1993年荷兰冠心病（CHD）生存率提高对患病率的影响进行了量化。
采用多阶段生命表拟合全国医院登记处的观察死亡率和登记率。结果为按年龄、性别、时期和疾病状态划分的患病率。
1980年至1993年冠心病的患病率为4.4%（25至84岁男性）和1.4%（25至84岁女性）。在1980 - 1983年和1990 - 1993年期间，发病率变化不大，但年龄调整后的患病率男性增加了19%，女性增加了59%。
冠心病死亡率急剧下降但发病率近乎恒定导致患病率显著上升，尤其是在老年人中。
