Kulczycki J
I Department of Neurology, Institute of Psychiatry and Neurology, Warszawa.
Folia Neuropathol. 1998;36(4):191-8.
The main trends are described in the studies of subacute sclerosing panencephalitis conducted in Poland or abroad with participation of Polish scientists. The history of these studies began in the years 1957-1959 with the works of Wender and Osetowska and ends presently at the end of our century with extinction of SSPE as a result of consistently conducted obligatory vaccinations against measles. The studies of Polish authors involved the problems of clinical diagnosis using immunological, electrophysiological and neurological imaging methods. Neuropathological problems were also studied extensively. Parallely with similar studies in the foremost foreign centres trials of SSPE treatment were undertaken in Poland, in recent years by means of intracerebroventricular administration of interferons. An original Polish method was the treatment with inducers of endogenous interferons. After the introduction of vaccinations against measles epidemiological studies repeated in the whole country were introduced for the assessment of the results of this preventive measure. These studies are regarded as model ones at international level.
在波兰科学家参与下于波兰或国外开展的亚急性硬化性全脑炎研究描述了主要趋势。这些研究的历史始于1957 - 1959年温德和奥塞托夫斯卡的著作，目前随着因持续开展强制性麻疹疫苗接种导致亚急性硬化性全脑炎灭绝而在本世纪末结束。波兰作者的研究涉及使用免疫、电生理和神经影像学方法进行临床诊断的问题。神经病理学问题也得到了广泛研究。与国外主要中心的类似研究同时，近年来波兰通过脑室内注射干扰素对亚急性硬化性全脑炎进行了治疗试验。一种原创的波兰方法是使用内源性干扰素诱导剂进行治疗。在引入麻疹疫苗接种后，在全国重复进行了流行病学研究以评估这一预防措施的效果。这些研究在国际层面被视为典范。
