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[自体骨软骨移植治疗关节软骨损伤]

[Autologous osteo-chondral grafts in the management of articular cartilage lesions].

作者信息

Bobic V

机构信息

Royal Liverpool University Hospitals, Broadgreen Hospital Knee Service.

出版信息

Orthopade. 1999 Jan;28(1):19-25. doi: 10.1007/s001320050317.

DOI:10.1007/s001320050317
PMID:10081040
Abstract

UNLABELLED

It is well known that the capacity of articular cartilage for repair is limited. There have been many attempts to address this problem. However, treatment options are limited and the long-term outcome is uncertain. This article will focus on the osteochondral autograft transplantation (OAT), which is currently the only surgical cartilage repair technique that provides and retains proper hyaline articular cartilage. Osteochondral autograft transplants have been associated with a good rate of success, but further long-term follow-up and biomechanical evaluation are essential.

LIMITATIONS

size and depth of osteochondral defects, availability of donor autologous grafts, potential for damaging donor sites, the dead spaces between circular grafts and integration of donor and recipient hyaline cartilage.

摘要

未标注

众所周知,关节软骨的修复能力有限。人们已经进行了许多尝试来解决这个问题。然而,治疗选择有限,长期结果也不确定。本文将重点关注自体骨软骨移植(OAT),这是目前唯一一种能够提供并保留正常透明关节软骨的手术软骨修复技术。自体骨软骨移植已取得了较高的成功率,但进一步的长期随访和生物力学评估至关重要。

局限性

骨软骨缺损的大小和深度、供体自体移植物的可用性、损伤供体部位的可能性、圆形移植物之间的死腔以及供体和受体透明软骨的整合。

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1
[Autologous osteo-chondral grafts in the management of articular cartilage lesions].[自体骨软骨移植治疗关节软骨损伤]
Orthopade. 1999 Jan;28(1):19-25. doi: 10.1007/s001320050317.
2
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3
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[Autologous osteochondral transplantation on various joints].
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Autologous chondrocyte implantation and osteochondral cylinder transplantation in cartilage repair of the knee joint. A prospective, comparative trial.自体软骨细胞移植与骨软骨柱移植用于膝关节软骨修复:一项前瞻性对照试验。
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Osteochondral Autologous Transplantation Compared to Microfracture for Treating Osteochondral Defect: An Updated Meta-analysis of Randomized Controlled Trials.自体骨软骨移植与微骨折术治疗骨软骨缺损的比较:随机对照试验的最新荟萃分析
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引用本文的文献

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Autologous Transplantation of Press-fit Bone Cylinders in the Treatment of Pelvic Nonunion.压配骨圆柱自体移植治疗骨盆骨不连。
Orthop Surg. 2019 Jun;11(3):516-523. doi: 10.1111/os.12463. Epub 2019 May 3.
2
Delayed gadolinium-enhanced MRI of cartilage and T2 mapping for evaluation of reparative cartilage-like tissue after autologous chondrocyte implantation associated with Atelocollagen-based scaffold in the knee.基于去细胞胶原蛋白支架的自体软骨细胞植入术后膝关节修复性软骨样组织评估的延迟钆增强磁共振成像及T2映射
Skeletal Radiol. 2016 Oct;45(10):1357-63. doi: 10.1007/s00256-016-2438-z. Epub 2016 Aug 2.
3
Influence of intra-articular administration of trichostatin a on autologous osteochondral transplantation in a rabbit model.
关节腔内注射曲古抑菌素A对兔自体骨软骨移植的影响。
Biomed Res Int. 2015;2015:470934. doi: 10.1155/2015/470934. Epub 2015 Mar 18.
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Matrix-induced autologous chondrocyte implantation (MACI) in the knee: clinical outcomes and challenges.膝关节基质诱导自体软骨细胞植入术(MACI):临床结果与挑战
Knee Surg Sports Traumatol Arthrosc. 2015 Dec;23(12):3729-35. doi: 10.1007/s00167-014-3295-8. Epub 2014 Sep 14.
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MR imaging of cartilage and its repair in the knee--a review.膝关节软骨及其修复的磁共振成像——综述
Eur Radiol. 2009 Jul;19(7):1582-94. doi: 10.1007/s00330-009-1352-3. Epub 2009 Mar 13.
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Results of chondrocyte implantation with a fibrin-hyaluronan matrix: a preliminary study.纤维蛋白-透明质酸基质软骨细胞植入的结果:一项初步研究。
Clin Orthop Relat Res. 2008 Aug;466(8):1849-55. doi: 10.1007/s11999-008-0322-4. Epub 2008 Jun 5.
7
[Autologous osteochondral transplants].[自体骨软骨移植]
Orthopade. 2008 Aug;37(8):734-42. doi: 10.1007/s00132-008-1263-z.
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[Five-year results following autogenous osteochondral transplantation to the femoral head].[自体骨软骨移植至股骨头后的五年结果]
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