植物血凝素与血清物质的结合及对霍奇金病淋巴细胞转化的抑制作用
Binding of phytohaemagglutinin to serum substances and inhibition of lymphocyte transformation in Hodgkin's disease.
作者信息
Amlot P L, Unger A
出版信息
Clin Exp Immunol. 1976 Dec;26(3):520-7.
Abstract
Serum from eleven of fifty-four patients with Hodgkin's disease inhibited phytohaemagglutinin (PHA) stimulation of both autologous and homologous lymphocytes. The inhibitory effect resided in the macromolecular fraction of these sera. PHA was shown to bind to serum substances in inhibitory sera and the degree of PHA binding in the macromolecular fraction correlated directly with the extent of inhibition.
摘要
54例霍奇金病患者中有11例的血清抑制了植物血凝素（PHA）对自体和同种淋巴细胞的刺激作用。这种抑制作用存在于这些血清的大分子部分。已证明PHA能与抑制性血清中的血清物质结合，大分子部分中PHA的结合程度与抑制程度直接相关。
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