Buchanan T W, al'Absi M, Lovallo W R
Veterans Affairs Medical Center, Oklahoma City, OK, USA.
Psychoneuroendocrinology. 1999 Feb;24(2):227-41. doi: 10.1016/s0306-4530(98)00078-x.
Prior studies have reported cortisol secretion to be primarily influenced by negative affect, but less is known about cortisol activity during states of activation involving increased positive affect and decreased negative affect. On separate days, 30 healthy young men experienced: an activating and humorous video; a speech stressor; and a resting control period. Cortisol was measured in saliva before and after each 30-min mood induction. Positive affect (activation) was increased similarly by both the video and the speech compared to rest (p < .0001). Negative affect increased during the speech and decreased during the video (p < .001). Cortisol increased only during the speech (p < .0001). Following the video, however, cortisol was decreased significantly (p < .0001). Rest day cortisol revealed no differences across periods (p > .1). These results suggest that the hypothalamic-pituitary-adrenocortical axis is a dynamic system influenced by changes in negative affect irrespective of the experience of generalized activation.
先前的研究报告称，皮质醇分泌主要受负面影响的影响，但对于涉及积极情绪增加和消极情绪减少的激活状态下的皮质醇活性，人们了解较少。在不同的日子里，30名健康的年轻男性经历了：一段具有启发性和幽默感的视频；一次演讲应激源；以及一个静息对照期。在每次30分钟的情绪诱导前后，测量唾液中的皮质醇。与静息状态相比，视频和演讲均使积极情绪（激活）同样增加（p <.0001）。消极情绪在演讲期间增加，在视频期间减少（p <.001）。皮质醇仅在演讲期间增加（p <.0001）。然而，观看视频后，皮质醇显著降低（p <.0001）。休息日的皮质醇在各时间段之间没有差异（p >.1）。这些结果表明，下丘脑-垂体-肾上腺皮质轴是一个动态系统，受消极情绪变化的影响，而与全身激活的体验无关。
