Bronstein I, Kricka L J
Clin Lab Manage Rev. 1990 Jul-Aug;4(4):303-5.
A key decision for clinical laboratory managers in the 1990s will be the type of detection system to adopt for immunoassays and DNA hybridization assays. It seems certain that assays based on radioactivity will not be desirable because of concerns about safety, stability of reagents, and environmental issues. Chemiluminescence is a prominent contender as the detection system of choice for both immunoassays and DNA hybridization tests. This article examines the features of various chemiluminescent reactions available and discusses the current range of commercial chemiluminescent test kits and reagents.
20世纪90年代临床实验室管理人员面临的一个关键决策将是为免疫测定和DNA杂交测定选择何种检测系统。由于对安全性、试剂稳定性和环境问题的担忧，基于放射性的测定似乎肯定不可取。化学发光作为免疫测定和DNA杂交测试的首选检测系统是一个突出的竞争者。本文研究了现有各种化学发光反应的特点，并讨论了当前市面上化学发光测试试剂盒和试剂的种类。
