Robieux I C, Kumar R, Rhadakrishnan S, Koren G
The Hospital for Sick Children, Toronto, Ontario.
Can J Hosp Pharm. 1990 Oct;43(5):235-6, xxxii.
EMLA is a eutectic mixture of local anaesthetics, lidocaine and prilocaine, effective in alleviating the pain of venous puncture in children. The lag time of 60 minutes, which is necessary to achieve effective anaesthesia after skin application, may be an important obstacle to the use of EMLA. In this study we recorded the routine practice of six pediatric outpatient clinics which may use EMLA. Our data show a large variability in the feasibility of using EMLA: In the Hematology-Oncology clinics 85% of the patients could benefit from EMLA without prolonging their hospital stay; in the Neurology clinic the mean waiting time is 60.2 +/- 45 minutes, and an additional 15 minutes would be required for only 26 percent of the patients. In four other clinics where the blood work is performed at the phlebotomy station, the waiting time before venous puncture ranges from five to 12 minutes and the use of EMLA would require major changes in the organization of the clinic, or a longer waiting time. In children suffering from chronic diseases, for whom painful medical procedures are a major cause of anxiety, the additional waiting time may be acceptable by both patients and their parents.
EMLA是一种局部麻醉剂利多卡因和丙胺卡因的共熔混合物,对减轻儿童静脉穿刺疼痛有效。皮肤涂抹后达到有效麻醉所需的60分钟滞后时间,可能是使用EMLA的一个重要障碍。在本研究中,我们记录了六个可能使用EMLA的儿科门诊的常规做法。我们的数据显示,使用EMLA的可行性差异很大:在血液肿瘤诊所,85%的患者可以从EMLA中受益,而不会延长住院时间;在神经科诊所,平均等待时间为60.2 +/- 45分钟,只有26%的患者还需要额外等待15分钟。在其他四个在采血站进行血液检查的诊所,静脉穿刺前的等待时间为5至12分钟,使用EMLA将需要对诊所的组织进行重大改变,或者等待更长时间。对于患有慢性病的儿童来说,痛苦的医疗程序是焦虑的主要原因,额外的等待时间可能患者及其父母都可以接受。