一种新型抗生素XK - 90。II. XK - 90的结构

A new antibiotic XK-90. II. The structure of XK-90.

作者信息

Takai H, Yoshida M, Iida T, Matsubara I, Shirahata K

出版信息

J Antibiot (Tokyo). 1976 Dec;29(12):1253-7. doi: 10.7164/antibiotics.29.1253.

DOI:10.7164/antibiotics.29.1253

Abstract

The new antibiotic, XK-90, produced by Streptomyces sp. is active against Gram-positive and Gram-negative bacteria. The structure has been determined as N-acetyl-N'-(3-formyl-4-hydroxyphenyl)hydrazine (1) and is the second example of a naturally occurring antibiotic having the phenylhydrazine skeleton.

摘要

链霉菌属产生的新型抗生素XK-90对革兰氏阳性菌和革兰氏阴性菌均有活性。其结构已确定为N-乙酰基-N'-(3-甲酰基-4-羟基苯基)肼(1)，是具有苯肼骨架的天然抗生素的第二个实例。