Grant D J, Al-Najjar T R
Microbios. 1976;15(61-62):177-89.
From garden soil a bacterium was isolated which grew aerobically in mineral salts medium with quinoline as sole C source and NH4+ as N source. During growth with quinoline, 2-hydroxyquinoline accumulated in the culture fluid and later disappeared. Whole cells oxidized 2-hydroxyquinoline, 2,6-dihydroxyquinoline and 2,7,8,-trihydroxyquinoline as rapidly as quinoline and without a lag. Catechol was oxidized more slowly by meta-cleavage but at an increasing rate indicative of adaptation. A number of derivatives of benzene and pyridine were not attacked. Whole cells oxidized 2,7,8,-trihydroxyquinoline to a yellow meta-cleavage product which was not further degraded. The following pathway is proposed: quinoline leads to 2-hydroxyquinoline leads to 2,6-dihydroxyquinoline leads to a trihydroxyquinoline (probably not the 2,7,8-compound, but possibly the 2,5,6-compound).
从花园土壤中分离出一种细菌，该细菌在以喹啉作为唯一碳源、NH4+作为氮源的无机盐培养基中好氧生长。在以喹啉生长期间，2-羟基喹啉在培养液中积累，随后消失。完整细胞氧化2-羟基喹啉、2,6-二羟基喹啉和2,7,8-三羟基喹啉的速度与氧化喹啉的速度一样快，且没有延迟。儿茶酚通过间位裂解氧化得较慢，但氧化速率不断增加，表明发生了适应性变化。苯和吡啶的许多衍生物未被攻击。完整细胞将2,7,8-三羟基喹啉氧化为一种黄色的间位裂解产物，该产物未进一步降解。提出了以下途径：喹啉生成2-羟基喹啉，2-羟基喹啉生成2,6-二羟基喹啉，2,6-二羟基喹啉生成一种三羟基喹啉（可能不是2,7,8-化合物，而是可能是2,5,6-化合物）。
