Aislabie J, Bej A K, Hurst H, Rothenburger S, Atlas R M
Department of Biology, University of Louisville, Kentucky 40292.
Appl Environ Microbiol. 1990 Feb;56(2):345-51. doi: 10.1128/aem.56.2.345-351.1990.
Several bacterial cultures were isolated that are able to degrade quinoline and to transform or to degrade methylquinolines. The degradation of quinoline by strains of Pseudomonas aeruginosa QP and P. putida QP produced hydroxyquinolines, a transient pink compound, and other undetermined products. The quinoline-degrading strains of P. aeruginosa QP and P. putida QP hydroxylated a limited number of methylquinolines but could not degrade them, nor could they transform 2-methylquinoline, isoquinoline, or pyridine. Another pseudomonad, Pseudomonas sp. strain MQP, was isolated that could degrade 2-methylquinoline. P. aeruginosa QP was able to degrade or to transform quinoline and a few methylquinolines in a complex heterocyclic nitrogen-containing fraction of a shale oil. All of the quinoline- and methylquinoline-degrading strains have multiple plasmids including a common 250-kilobase plasmid. The 225-, 250-, and 320-kilobase plasmids of the P. aeruginosa QP strain all contained genes involved in quinoline metabolism.
分离出了几种能够降解喹啉并转化或降解甲基喹啉的细菌培养物。铜绿假单胞菌QP菌株和恶臭假单胞菌QP菌株对喹啉的降解产生了羟基喹啉、一种短暂的粉红色化合物以及其他未确定的产物。铜绿假单胞菌QP菌株和恶臭假单胞菌QP菌株的喹啉降解菌株使有限数量的甲基喹啉羟基化，但无法降解它们，也不能转化2-甲基喹啉、异喹啉或吡啶。分离出了另一种假单胞菌，假单胞菌属菌株MQP，它能够降解2-甲基喹啉。铜绿假单胞菌QP能够降解或转化页岩油复杂含氮杂环馏分中的喹啉和一些甲基喹啉。所有降解喹啉和甲基喹啉的菌株都有多个质粒，包括一个常见的250千碱基质粒。铜绿假单胞菌QP菌株的225、250和320千碱基质粒都含有参与喹啉代谢的基因。
