[病毒性肝炎患者的假尿苷与尿酸排泄]
[Pseudouridine and uric acid excretion in patients with viral hepatitis].
作者信息
Lifshits R I, Salomatin V V, Efimenko G P
出版信息
Vopr Med Khim. 1976 Sep-Oct;22(5):687-90.
PMID:1014482
Abstract
Daily excretion of pseudouridine and uric acid with urine was studied in healthy persons and in patients with viral hepatitis during various periods of the disease. Excretion of pseudouridine was increased 2.5-fold and of uric acid--2-fold within the acute period of the disease. The degree of impairment in nucleic acids metabolism could be estimated by measuring of excretion of pseudouridine and uric acid and by calculation of their ratio during various periods of the disease.
摘要
研究了健康人和病毒性肝炎患者在疾病不同阶段尿中假尿苷和尿酸的每日排泄量。在疾病急性期，假尿苷排泄量增加了2.5倍，尿酸排泄量增加了2倍。通过测量疾病不同阶段假尿苷和尿酸的排泄量及其比值，可以评估核酸代谢的受损程度。
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