枯草芽孢杆菌中抗衣霉素突变体及突变位点的染色体定位
Tunicamycin-resistant mutants and chromosomal locations of mutational sites in Bacillus subtilis.
作者信息
Nomura S, Yamane K, Sasaki T, Yamasaki M, Tamura G, Maruo B
出版信息
J Bacteriol. 1978 Nov;136(2):818-21. doi: 10.1128/jb.136.2.818-821.1978.
Abstract
The types of tunicamycin-resistant mutants of Bacillus subtilis were analyzed, and their mutational sites on the chromosome were mapped. A type 1 mutation that simultaneously expressed hyperproductivity of extracellular alpha-amylase was located close to amy E. Type 2 mutations were near aroI.
摘要
对枯草芽孢杆菌抗衣霉素突变体的类型进行了分析，并绘制了它们在染色体上的突变位点。一种同时表现出细胞外α-淀粉酶高产的1型突变位于靠近amy E的位置。2型突变位于aroI附近。
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本文引用的文献
1
PREPARATION OF TRANSFORMING DEOXYRIBONUCLEIC ACID BY PHENOL TREATMENT.
Biochim Biophys Acta. 1963 Aug 20;72:619-29.
2
Tunicamycin, a new antibiotic. I. Isolation and characterization of tunicamycin.
J Antibiot (Tokyo). 1971 Apr;24(4):215-23. doi: 10.7164/antibiotics.24.215.
3
Temperature-sensitive mutants of Bacillus subtilis. I. Multiforked replication and sequential transfer of DNA by a temperature-sensitive mutant.
Proc Natl Acad Sci U S A. 1970 Jan;65(1):206-13. doi: 10.1073/pnas.65.1.206.
4
Chromosomal location of genes regulating resistance to bacteriophage in Bacillus subtilis.
J Bacteriol. 1969 Jun;98(3):1087-97. doi: 10.1128/jb.98.3.1087-1097.1969.
5
On the gene controlling the rate of amylase production in Bacillus subtilis.
Biochem Biophys Res Commun. 1968 Apr 19;31(2):182-7. doi: 10.1016/0006-291x(68)90727-4.
6
Purification and properties of a cross-reacting material related to -amylase and biochemical comparison with the parent -amylase.
Biochim Biophys Acta. 1973 Jan 25;295(1):323-40. doi: 10.1016/0005-2795(73)90100-1.
7
Isolation of mutants defective in alpha-amylase from Bacillus subtilis: genetic analyses.
J Bacteriol. 1974 Aug;119(2):416-24. doi: 10.1128/jb.119.2.416-424.1974.
8
Tunicamycin inhibition of bacterial wall polymer synthesis.
FEBS Lett. 1977;78(1):151-4. doi: 10.1016/0014-5793(77)80294-9.
9
Mapping of mutations affecting synthesis of exocellular enzymes in Bacillus subtilis. Identity of the sacUh, amyB and pap mutations.
Mol Gen Genet. 1976 Nov 17;148(3):281-5. doi: 10.1007/BF00332902.
10
Hyperproductivity of extracellular alpha-amylase by a tunicamycin resistant mutant of Bacillus subtilis.
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