Regnier F E, He B, Lin S, Busse J
Purdue University, West Lafayette, IN 47907, USA.
Trends Biotechnol. 1999 Mar;17(3):101-6. doi: 10.1016/s0167-7799(98)01294-3.
Liquid chromatography and electrophoresis played a major role in the life-science revolution, most strikingly in protein purification, peptide fractionation and sequencing, amino acid analysis, and DNA sequencing. The objective of this article is to examine the potential role of separation systems in the continuing evolution of biochemistry, biotechnology and molecular biology. Very small chip-based systems may change how chemical analyses in biology, medical research and health care evolve over the next decade.