Ginsburg E, Livshits G
Tel Aviv University, Israel.
Ann Hum Biol. 1999 Mar-Apr;26(2):103-29. doi: 10.1080/030144699282822.
A review of advanced methods of segregation analysis of quantitative traits on human pedigree data is presented. Special attention was paid to formulation of genetic models tested in the analysis, to the possibility of statistical distinguishing between these models, to the power of the used transmission probability tests, and to the possibility of unambiguous interpretation of the analysis results.
本文对人类家系数据中数量性状分离分析的先进方法进行了综述。特别关注了分析中所测试的遗传模型的构建、这些模型之间进行统计区分的可能性、所用传递概率检验的功效以及分析结果进行明确解释的可能性。