Zhao Q, Zhai G J, Ng D H, Zhang X Z, Chen Z Q
Department of Physics, Chinese University of Hong Kong, Shatin, China.
Biomaterials. 1999 Mar;20(6):595-9. doi: 10.1016/s0142-9612(98)00218-x.
Ion implantation technique was applied to graft the -NH2 amidogen radicals onto the surface of Al2O3 bioceramic. Fourier transform infrared spectroscopy (FTIR) was used to confirm the presence of the implanted radicals on the Al2O3 ceramic surface. It was found that the amount of grafted amidogen radicals was proportional to the dosage of NH2+ ions used during the ion implantation. Furthermore, when implantation energy of 100 keV was used, maximum amount of -NH2 radicals would be grafted on the Al2O3 ceramic surface. The biocompatibility of the implanted Al2O3 ceramic was also investigated, and the results indicate that the implanted surface has better biocompatibility with animal bone tissue than the plain ceramic surface.
