Franco A M, Grimaldi G
Instituto Oswaldo Cruz, Rio de Janeiro, RJ, 21045-900, Brasil.
Mem Inst Oswaldo Cruz. 1999 Mar-Apr;94(2):261-8. doi: 10.1590/s0074-02761999000200026.
This article reviews current concepts of the biology of Endotrypanum spp. Data summarized here on parasite classification and taxonomic divergence found among these haemoflagellates come from our studies of molecular characterization of Endotrypanum stocks (representing an heterogenous population of reference strains and isolates from the Brazilian Amazon region) and from scientific literature. Using numerical zymotaxonomy we have demonstrated genetic diversity among these parasites. The molecular trees obtained revealed that there are, at least, three groups (distinct species?) of Endotrypanum, which are distributed in Central and South America. In concordance with this classification of the parasites there are further newer molecular data obtained using distinct markers. Moreover, comparative studies (based on the molecular genetics of the organisms) have shown the phylogenetic relationships between some Endotrypanum and related kinetoplastid lineages.
本文综述了锥虫属生物的当前概念。此处总结的关于这些血鞭毛虫的寄生虫分类和分类学差异的数据，来自我们对锥虫种群（代表来自巴西亚马逊地区的参考菌株和分离株的异质群体）的分子特征研究以及科学文献。通过数值酶谱分类法，我们证明了这些寄生虫之间的遗传多样性。得到的分子树显示，至少有三组（不同的物种？）锥虫，分布在中美洲和南美洲。与这种寄生虫分类相一致的是，使用不同标记获得了更新的分子数据。此外，（基于生物体分子遗传学的）比较研究显示了一些锥虫与相关动基体谱系之间的系统发育关系。
