Uzun S, Uslular C, Yücel A, Acar M A, Ozpoyraz M, Memişoğlu H R
Department of Dermatology and Tropical Disease Research Centre, Faculty of Medicine, Cukurova University, 01330 Adana, Turkey.
Br J Dermatol. 1999 Feb;140(2):347-50. doi: 10.1046/j.1365-2133.1999.02673.x.
A total of 3,074 cases of cutaneous leishmaniasis was evaluated for demography, diagnosis, clinical characteristics and treatment. A peak in the number of cases was observed in 1991 and 1992, with a total of 1,550 cases. There were seasonal differences in frequency, the highest levels being recorded during the period October-December each year. The disease was more frequent in females (59%) and in the age group 10-19 years (41%). More than 80% of 4394 lesions were located on exposed body sites, and most patients (87%) had the acute form of the disease. Diagnosis was made by the smear method in 90% of cases. Treatment was by intralesional injection of antimony compounds in 76% of cases. Cryotherapy was used in most of the remaining cases, either alone or combined with intralesional injection of antimony compounds. The overall healing rate was over 90%.
共对3074例皮肤利什曼病患者进行了人口统计学、诊断、临床特征及治疗方面的评估。1991年和1992年病例数出现高峰,共有1550例。发病频率存在季节性差异,每年10月至12月记录的发病水平最高。该病在女性中更为常见(59%),在10 - 19岁年龄组中最为高发(41%)。4394处皮损中超过80%位于身体暴露部位,大多数患者(87%)患的是急性病。90%的病例通过涂片法确诊。76%的病例采用病灶内注射锑化合物进行治疗。其余大多数病例单独或联合病灶内注射锑化合物使用冷冻疗法。总体治愈率超过90%。