Hottenrott C, Seufert R, Kühne F, Gerstenbergk L
Chir Forum Exp Klin Forsch. 1977 Apr:221-3.
15 mini-pigs were bled to a mean aortic blood-pressure of 40 mm Hg, which was sustained for 3 hours. 2 groups were studied: Control-Group: Shock alone without splanchnicectomy (n = 8); Test-Group: Shock after splanchnicectomy 14 days previously (n = 7). In all animals a stimulated gastric secretion test was performed 3 days before and 8 days after this operation. All animals of the control-group showed severe gastric mucosal lesions after shock. Piglets with splanchnicectomy (test-group), conversely, developed no (5 animals) or only minor changes (2 animals). The efficiency of splanchnicectomy was proved by a stimulated gastric secretion test: Basal acid output did not change after operation, peak acid output however increased significantly. This study in piglets shows, that splanchnicectomy of the stomach prevents gastric stress-lesions almost completely.
将15只小型猪放血，使平均主动脉血压降至40毫米汞柱，并持续3小时。研究了2组：对照组：单纯休克，未进行内脏切除术（n = 8）；试验组：14天前进行内脏切除术后休克（n = 7）。在所有动物中，在该手术前3天和术后8天进行了刺激胃分泌试验。对照组所有动物在休克后均出现严重胃黏膜损伤。相反，进行了内脏切除术的仔猪（试验组）未出现（5只动物）或仅出现轻微变化（2只动物）。通过刺激胃分泌试验证明了内脏切除术的效果：术后基础胃酸分泌量未改变，但高峰胃酸分泌量显著增加。对仔猪的这项研究表明，胃的内脏切除术几乎可以完全预防胃应激性损伤。
