Royle J, Halasz S, Eagles G, Gilbert G, Dalton D, Jelfs P, Isaacs D
Department of Immunology and Infectious Diseases, Royal Alexandra Hospital for Children, NSW, Australia.
Arch Dis Child Fetal Neonatal Ed. 1999 Jan;80(1):F64-8. doi: 10.1136/fn.80.1.f64.
An outbreak of extended spectrum beta lactamase producing Klebsiella pneumoniae (ESBLKp) in a neonatal unit was controlled using simple measures. Normally, the control of such infections can be time consuming and expensive. Seven cases of septicaemia resulted in two deaths. ESBLKp isolates were subtyped by pulsed field gel electrophoresis, and four of the five isolates typed were identical. Control of the outbreak was achieved by altered empiric antibiotic treatment for late onset sepsis and prevention of cross infection by strict attention to hand washing. Widespread colonisation of babies in the unit was presumed, so initial surveillance cultures were not performed. No further episodes of sepsis occurred.
在一个新生儿病房中，通过简单措施控制了产超广谱β-内酰胺酶肺炎克雷伯菌（ESBLKp）的暴发。通常，控制此类感染可能既耗时又昂贵。七例败血症导致两例死亡。通过脉冲场凝胶电泳对ESBLKp分离株进行亚型分析，五个分型的分离株中有四个是相同的。通过改变对晚发性败血症的经验性抗生素治疗以及严格注意洗手来预防交叉感染，实现了疫情的控制。假定该病房的婴儿普遍存在定植，因此未进行初始监测培养。此后未再发生败血症病例。
