Lebessi E, Dellagrammaticas H, Tassios P T, Tzouvelekis L S, Ioannidou S, Foustoukou M, Legakis N J
Department of Microbiology, Neonatal Intensive Care Unit, P. & A. Kyriakou Children's Hospital, University of Athens, Athens, Greece.
J Clin Microbiol. 2002 Mar;40(3):799-804. doi: 10.1128/JCM.40.3.799-804.2002.
Extended-spectrum beta-lactamase-producing Klebsiella pneumoniae (EPKP) strains are frequently implicated in outbreaks in neonatal intensive care units (NICUs). During the period from 1997 to 1998, 21 infections and 23 colonizations with EPKP were recorded in the NICU of a children's hospital in Athens, Greece. Seventeen of the infected and 12 of the colonized neonates had been referred from other hospitals. The remaining infections and colonizations occurred during the current hospitalization. Pulsed-field gel electrophoresis typing showed that the latter cases were due to an outbreak strain that persisted in the unit, while the repeated introduction of EPKP carriers was mostly due to clonal outbreaks in two maternity hospitals.
产超广谱β-内酰胺酶的肺炎克雷伯菌（EPKP）菌株常与新生儿重症监护病房（NICU）的暴发有关。在1997年至1998年期间，希腊雅典一家儿童医院的新生儿重症监护病房记录了21例由EPKP引起的感染和23例定植。17例感染新生儿和12例定植新生儿是从其他医院转诊而来。其余感染和定植发生在本次住院期间。脉冲场凝胶电泳分型显示，后一种情况是由于一种在该病房持续存在的暴发菌株引起的，而EPKP携带者的反复引入主要是由于两家妇产医院的克隆暴发。
