Graham B, Judge S J
University Laboratory of Physiology, Oxford, UK.
Vision Res. 1999 Jan;39(2):177-87. doi: 10.1016/s0042-6989(98)00188-6.
Refractive state and ocular dimensions were studied longitudinally in nine normal marmosets. Animals were anaesthetised and examined (with some exceptions) at 4, 6, 7, 8, 10, 15, 24 and 39 weeks of age. Cycloplegic retinoscopy showed that hyperopia early in life rapidly diminished. Refraction corrected for the artefact of retinoscopy stabilised by 8 weeks of age, but at a slightly myopic value, rather than at emmetropia. The ocular components continued to change throughout the period studied. Corneal radius, measured by photokeratometry, increased slightly during development. Anterior segment depth and vitreous chamber depth (VCD), measured by A-scan ultrasonography, increased throughout development while lens thickness initially increased and then decreased. Data from the eyes of these normal animals were compared with that from the contralateral eyes of animals which received short periods of monocular deprivation early in life (Troilo, D., & Judge S.J. (1993). Ocular development and visual deprivation myopia in the common marmoset (Callithrix jacchus jacchus). Vision Research, 33, 1311-24); eyes which viewed through no lens or a plano lens (Graham, B. & Judge, S.J. (1999)). The effects of spectacle wear in infancy on eye growth and refractive error in the marmoset (Callithrix jacchus). Vision Research, 39, 189-206), and eyes of normal animals in another colony. There were no significant differences between the first two groups and the normal animals in our colony while age-matched animals from the other colony were slightly but significantly less myopic than our animals.
对9只正常狨猴的屈光状态和眼尺寸进行了纵向研究。在动物4、6、7、8、10、15、24和39周龄时进行麻醉检查（有一些例外情况）。睫状肌麻痹视网膜检影法显示，生命早期的远视迅速减轻。校正视网膜检影伪差后的屈光度在8周龄时稳定下来，但处于轻度近视值，而非正视。在所研究的整个时期内，眼部各组成部分持续变化。通过光角膜测量法测量的角膜半径在发育过程中略有增加。通过A超超声检查测量的前段深度和玻璃体腔深度（VCD）在整个发育过程中增加，而晶状体厚度最初增加然后减少。将这些正常动物眼睛的数据与生命早期接受短期单眼剥夺的动物对侧眼的数据进行比较（Troilo, D., & Judge S.J. (1993). 普通狨猴（Callithrix jacchus jacchus）的眼发育和视觉剥夺性近视。《视觉研究》, 33, 1311 - 24）；通过无晶状体或平光镜观察的眼睛（Graham, B. & Judge, S.J. (1999). 婴儿期戴眼镜对狨猴（Callithrix jacchus）眼生长和屈光不正的影响。《视觉研究》, 39, 189 - 206），以及另一个群体中正常动物的眼睛。前两组与我们群体中的正常动物之间没有显著差异，而来自另一个群体且年龄匹配的动物比我们的动物近视程度略低但有显著差异。
