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恶性疟原虫疫苗接种的三带犰狳对异源菌株攻击的部分保护作用。

Partial protection of Plasmodium falciparum-vaccinated Aotus trivirgatus against a challenge of a heterologous strain.

作者信息

Siddiqui W A, Taylor D W, Kan S C, Kramer K, Richmond-Crum S

出版信息

Am J Trop Med Hyg. 1978 Nov;27(6):1277-8. doi: 10.4269/ajtmh.1978.27.1277.

DOI:10.4269/ajtmh.1978.27.1277
PMID:103450
Abstract

Two Aotus trivirgatus griseimenbra monkeys which had been immunized with the merozoite-enriched FUP strain of Plasmodium falciparum were protected against a primary challenge with the homologous strain. The results described here show that these two monkeys were protected against a subsequent challenge with a heterologous strain (FVO) of P. falciparum. The unimmunized control monkey died of FVO infection by day 18.

摘要

两只曾用富含裂殖子的恶性疟原虫FUP株免疫的小三带犰狳猴对同源株的初次攻击具有抵抗力。此处描述的结果表明,这两只猴子对随后恶性疟原虫异源株(FVO)的攻击也具有抵抗力。未免疫的对照猴在第18天死于FVO感染。

相似文献

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Partial protection of Plasmodium falciparum-vaccinated Aotus trivirgatus against a challenge of a heterologous strain.恶性疟原虫疫苗接种的三带犰狳对异源菌株攻击的部分保护作用。
Am J Trop Med Hyg. 1978 Nov;27(6):1277-8. doi: 10.4269/ajtmh.1978.27.1277.
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Merozoite surface coat precursor protein completely protects Aotus monkeys against Plasmodium falciparum malaria.裂殖子表面被膜前体蛋白可使夜猴完全抵御恶性疟原虫疟疾。
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Immunization of experimental monkeys against Plasmodium falciparum: use of synthetic adjuvants.用合成佐剂对实验猴进行恶性疟原虫免疫接种
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Protection of Aotus monkeys after immunization with recombinant antigens of Plasmodium falciparum.用恶性疟原虫重组抗原免疫后对夜猴的保护作用。
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An effective immunization of Aotus trivirgatus monkeys against Plasmodium falciparum: a research note.对三带犰狳猴进行针对恶性疟原虫的有效免疫:一项研究笔记。
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Repeated infection of Aotus monkeys with Plasmodium falciparum induces protection against subsequent challenge with homologous and heterologous strains of parasite.将食蟹猴反复感染恶性疟原虫可诱导其对随后同源和异源疟原虫株的攻击产生保护作用。
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An effective immunization of experimental monkeys against a human malaria parasite, Plasmodium falciparum.对实验猴进行针对人类疟原虫恶性疟原虫的有效免疫接种。
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Passive transfer of growth-inhibitory antibodies raised against yeast-expressed recombinant Plasmodium falciparum merozoite surface protein-1(19).针对酵母表达的重组恶性疟原虫裂殖子表面蛋白-1产生的生长抑制性抗体的被动转移(19)。
Am J Trop Med Hyg. 1998 Dec;59(6):991-7. doi: 10.4269/ajtmh.1998.59.991.

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