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癫痫犬的脑电图:人与犬研究结果的相似性

Electroencephalography in dogs with epilepsy: similarities between human and canine findings.

作者信息

Berendt M, Høgenhaven H, Flagstad A, Dam M

机构信息

Dept of Clinical Studies, Small Animal Hospital, The Royal Veterinary and Agricultural University, Copenhagen, Denmark.

出版信息

Acta Neurol Scand. 1999 May;99(5):276-83. doi: 10.1111/j.1600-0404.1999.tb00676.x.

DOI:10.1111/j.1600-0404.1999.tb00676.x
PMID:10348156
Abstract

OBJECTIVES

To investigate the diagnostic value of electroencephalography (EEG) in dogs with epilepsy, applying human criteria for EEG abnormalities observed with this disorder.

MATERIAL AND METHODS

Twenty-six dogs with a clinically established diagnosis of epilepsy were investigated with electroencephalography (EEG) in order to evaluate the diagnostic yield of EEG in canine epilepsy.

RESULTS

Of 23 dogs with evaluable EEGs 15 (65%) demonstrated abnormal activity. The most common abnormalities were focal low frequency patterns without spikes (48%), followed by focal epileptiform activity (22%) and generalized epileptiform activity (17%). The distribution between focal and generalized activity were 73% and 27%, respectively. Consistency were demonstrated between the clinical- and the EEG-diagnosis in 13 dogs (87%). A relationship was demonstrated between the number of abnormal EEGs and the proximity of a seizure to the EEG examination.

CONCLUSION

A marked consistency was demonstrated between the clinical diagnosis of seizure type and the type of abnormalities observed in the EEG, thus indicating that EEG is a valuable diagnostic aid in confirming the diagnosis of epilepsy in dogs. EEG findings in dogs with epilepsy and humans with this disorder were markedly similar.

摘要

目的

应用人类癫痫疾病中观察到的脑电图(EEG)异常标准,研究脑电图在犬癫痫中的诊断价值。

材料与方法

对26只临床确诊为癫痫的犬进行脑电图(EEG)检查,以评估脑电图在犬癫痫中的诊断率。

结果

在23只可评估脑电图的犬中,15只(65%)表现出异常活动。最常见的异常是无棘波的局灶性低频模式(48%),其次是局灶性癫痫样活动(22%)和全身性癫痫样活动(17%)。局灶性和全身性活动的分布分别为73%和27%。13只犬(87%)的临床诊断和脑电图诊断之间具有一致性。脑电图异常数量与癫痫发作距脑电图检查的时间间隔之间存在关联。

结论

癫痫发作类型的临床诊断与脑电图中观察到的异常类型之间显示出明显的一致性,因此表明脑电图是确诊犬癫痫的有价值的诊断辅助手段。犬癫痫和人类癫痫患者的脑电图结果明显相似。

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