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[护理学院学生的结核菌素皮肤试验]

[Tuberculin skin testing in students of school of nursing].

作者信息

Shigeto E

机构信息

National Hiroshima Hospital, Japan.

出版信息

Kekkaku. 1999 Apr;74(4):421-3.

Abstract

Tuberculin skin testing in students of the School of Nursing Attached to National Hiroshima Hospital was analyzed. On initial test using 0.05 microgram of PPDs, diameter of erythema in 26.7% of 300 new students were less than 9 mm. Twelve of 24 who were tested by two-step method reacted more than 10 mm on the second test. Twenty-seven non-reactors who were vaccinated with BCG all reacted more than 10 mm after 9 to 16 weeks after vaccination. They might be vaccinated in the past by insufficient technique and better be revaccinated. Thirty-one of 49 students who graduated in 1998 were tested and their reactions were compared with those on entrance or after BCG vaccination. The two tests were spaced 31 to 34 months apart. The reactions were weakened in the cases after BCG vaccination, and in those who were not vaccinated on entrance, only a little booster effect were observed, except in 3 graduates whose reactions were significantly boosted and thought to be infected while in school. As there is considerable variation in tuberculin reactivity after BCG vaccination, diameter of reaction should be kept on personal health record as base line reaction to diagnose tuberculous infection henceforce.

摘要

对广岛国立医院附属护理学校的学生进行了结核菌素皮肤试验分析。在首次使用0.05微克结核菌素纯蛋白衍生物(PPDs)进行测试时,300名新生中有26.7%的人红斑直径小于9毫米。采用两步法检测的24人中,有12人在第二次测试时反应超过10毫米。27名接种过卡介苗的无反应者在接种后9至16周,所有反应均超过10毫米。他们过去可能接种技术不足,最好重新接种。对1998年毕业的49名学生中的31人进行了测试,并将他们的反应与入学时或接种卡介苗后的反应进行了比较。两次测试间隔31至34个月。接种卡介苗后的反应减弱,入学时未接种的学生中,除3名毕业生反应明显增强且被认为在校期间感染外,仅观察到轻微的增强效应。由于接种卡介苗后结核菌素反应性存在相当大的差异,今后应将反应直径记录在个人健康记录中,作为诊断结核感染的基线反应。

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