Campbell R L, Ross G A, Campbell J R, Mourino A P
Department of Oral and Maxillofacial Surgery, Virginia Commonwealth University, Medical College of Virginia, Richmond 23298, USA.
Anesth Prog. 1998 Spring;45(2):46-50.
Fifteen consecutive pediatric patients ranging from 3 to 5 years old were selected to receive one of three sedative/hypnotic techniques. Group 1 received oral chloral hydrate 50 mg/kg, and groups 2 and 3 received intramuscular ketamine 2 mg/kg and 3 mg/kg, respectively. In addition to ketamine, patients in groups 2 and 3 received transmucosal intramuscular injections of meperidine and promethazine into the masseter muscle. Sedation for the satisfactory completion of restorative dentistry was obtained for over 40 min on average in the chloral hydrate group, but completion of dental surgery longer than 40 min was achieved in groups 2 and 3 only by intravenous supplements of ketamine.
选取了15名年龄在3至5岁之间的连续儿科患者，让他们接受三种镇静/催眠技术中的一种。第1组口服50毫克/千克水合氯醛，第2组和第3组分别肌肉注射2毫克/千克和3毫克/千克氯胺酮。除氯胺酮外，第2组和第3组患者还通过经粘膜向咬肌注射哌替啶和异丙嗪。水合氯醛组平均超过40分钟就能获得满意的镇静效果以完成修复性牙科治疗，但只有第2组和第3组通过静脉补充氯胺酮才能完成超过40分钟的牙科手术。
