Cancer Prevention Institute of California, Berkeley, California, USA.
Am J Epidemiol. 2010 Sep 15;172(6):691-9. doi: 10.1093/aje/kwq190. Epub 2010 Aug 6.
Health concerns have been pronounced for cosmetologists and manicurists, who are exposed daily to cosmetic products containing known or suspected human carcinogens and endocrine disruptors. In this retrospective cohort study, the authors used probabilistic record linkage between California's statewide cosmetology licensee and cancer surveillance files to identify newly diagnosed invasive cancers among female workforce members during 1988-2005. Rate ratios and 95% confidence intervals for cancer among workforce members compared with the general female population in California were estimated via Poisson regression. For comparison, site-specific proportional incidence ratios were computed. The authors identified 9,044 cancer cases in a cohort of 325,228 licensees. Rate ratios for all sites combined suggested lower incidence among both cosmetologists (rate ratio = 0.84, 95% confidence interval (CI): 0.82, 0.86) and manicurists (rate ratio = 0.87, 95% CI: 0.84, 0.90). Proportional incidence ratios were modestly elevated for thyroid cancer among all licensees (proportional incidence ratio = 1.13, 95% CI: 1.04, 1.23) and for lung cancer among manicurists (proportional incidence ratio = 1.21, 95% CI: 1.07, 1.36). Although there did not appear to be a cancer excess, these findings may be artifactually influenced by limitations in demographic information available from the licensee files. Additionally, the relatively young ages of cohort members and demographic shifts in the industry composition in recent years suggest a need for further follow-up.
健康问题已经引起了美容师和美甲师的关注，他们每天都接触到含有已知或疑似人类致癌物和内分泌干扰物的化妆品。在这项回顾性队列研究中，作者使用加利福尼亚州全州范围内的美容师执照和癌症监测档案之间的概率记录链接，来识别 1988 年至 2005 年期间女性劳动力成员中新诊断的侵袭性癌症。通过泊松回归估计了与加利福尼亚州一般女性人群相比，劳动力成员中癌症的比率比和 95%置信区间。为了比较，还计算了特定部位的比例发病率比。作者在 325228 名持照者的队列中确定了 9044 例癌症病例。所有部位综合的比率比表明，美容师（比率比=0.84，95%置信区间（CI）：0.82，0.86）和美甲师（比率比=0.87，95%CI：0.84，0.90）的发病率较低。所有持照者的甲状腺癌（比例发病率比=1.13，95%CI：1.04，1.23）和美甲师的肺癌（比例发病率比=1.21，95%CI：1.07，1.36）的比例发病率比略有升高。尽管似乎没有癌症过多，但这些发现可能会受到从持照者档案中获得的人口统计学信息的限制的人为影响。此外，由于近年来队列成员年龄相对较小以及行业构成的人口统计学变化，因此需要进一步跟踪随访。
