Simmers T A, Jie C, Sie B
Department of Pulmonology, St. Lucas Andreas Hospital, Amsterdam, The Netherlands.
Thorac Cardiovasc Surg. 1999 Apr;47(2):77-81. doi: 10.1055/s-2007-1013115.
The present study was undertaken to assess the efficacy of serial thoracocentesis and saline irrigation for the treatment of pleural empyema, for post-pneumonia versus other causes.
Included were 42 consecutive patients with complicated pleural effusion (n=14) or frank pus (n=28) at diagnostic thoracocentesis, of mean age 57.5 +/- 23.7 years. Pneumonia was the probable cause in 29 patients, other causes (principally thoracic surgery) in 13. In addition to antibiotics in all patients, ultrasonography-guided serial suction thoracocentesis with saline irrigation was used as therapy of first choice in most patients: 28/29 post-pneumonia and 9/13 non-pneumonic empyema. Exceptions were mainly on the grounds of preceding thoracic surgery.
Success rate was 86% in the post-pneumonia group, with no crossovers to more invasive therapy. Mortality was 14%, none empyema-related. Treatment was less successful in the non-pneumonia group at 69%, with a 56% crossover rate from thoracocentesis due to therapy failure. Mortality was 23 %.
Results indicate that timely, minimally invasive therapy is a feasible modality for the management of post-pneumonia thoracic empyema. Serial thoracocentesis was less suitable for the treatment of non-pneumonic empyema, however, particularly if it was a surgical complication. More invasive strategies seem preferable in such cases.
本研究旨在评估胸腔穿刺抽液并生理盐水灌洗治疗胸腔积脓的疗效,比较肺炎后胸腔积脓与其他原因所致胸腔积脓的治疗效果。
纳入42例诊断性胸腔穿刺时出现复杂性胸腔积液(n = 14)或明显脓液(n = 28)的连续患者,平均年龄57.5±23.7岁。29例患者可能病因是肺炎,13例患者病因是其他原因(主要是胸外科手术)。除所有患者均使用抗生素外,多数患者(28/29例肺炎后胸腔积脓患者和9/13例非肺炎性胸腔积脓患者)首选超声引导下胸腔穿刺抽液并生理盐水灌洗治疗。例外情况主要是基于先前的胸外科手术史。
肺炎后胸腔积脓组成功率为86%,无患者转为更具侵入性的治疗。死亡率为14%,均与胸腔积脓无关。非肺炎组治疗成功率为69%,因治疗失败,56%的患者由胸腔穿刺治疗转为其他治疗。死亡率为23%。
结果表明,及时、微创治疗是管理肺炎后胸腔积脓的可行方式。然而,胸腔穿刺抽液不太适合治疗非肺炎性胸腔积脓,尤其是手术并发症导致的胸腔积脓。在这种情况下,更具侵入性的策略似乎更可取。