Menéndez C, Sánchez-Tapias J M, Alonso P L, Giménez-Barcons M, Kahigwa E, Aponte J J, Mshinda H, Navia M M, Jiménez de Anta M T, Rodés J, Saiz J C
Liver Unit, Department of Medicine, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clinic, Barcelona, Spain.
J Clin Microbiol. 1999 Jul;37(7):2333-6. doi: 10.1128/JCM.37.7.2333-2336.1999.
Hepatitis G virus (HGV) RNA was detected in 18 of 133 pregnant women from Tanzania without known risk factors for HGV infection and in 7 of 18 children born to HGV RNA-positive mothers. Molecular evidence of mother-to-infant transmission was obtained only for three of seven children. HGV RNA was also detected in 4 of 42 children born to non-HGV-infected women. Thus, mechanisms other than materno-filial may play an important role in HGV transmission during early childhood.
在坦桑尼亚133名无已知庚型肝炎病毒(HGV)感染风险因素的孕妇中,有18人检测出HGV RNA;在18名HGV RNA阳性母亲所生的孩子中,有7人检测出HGV RNA。仅在7名儿童中的3名儿童身上获得了母婴传播的分子证据。在42名非HGV感染女性所生的儿童中,也有4人检测出HGV RNA。因此,除母婴传播外的其他机制可能在儿童早期HGV传播中起重要作用。