Dietlein T S, Jacobi P C, Krieglstein G K
Department of Ophthalmology, University of Cologne, Germany.
Br J Ophthalmol. 1999 Mar;83(3):317-22. doi: 10.1136/bjo.83.3.317.
The strategy of pressure reducing surgery in primary congenital glaucoma has changed over the last decade. Ab externo filtering procedures--for example, trabeculectomy or trabeculotomy combined with trabeculectomy, have now been accepted even as primary intervention.
The authors reviewed 61 eyes in 35 consecutive patients with primary congenital glaucoma, who underwent different types of initial ab externo surgery between 1988 and 1996 (median follow up 36 months) to determine the efficacy of different surgical techniques and the influence of various risk factors.
Trabeculotomy was performed in 17 eyes (27.9%), trabeculotomy with trabeculectomy in 15 eyes (24.6%), and trabeculectomy in 29 eyes (47.5%). Regarding age, preoperative intraocular pressure, corneal diameter, ocular axial length, and incidence of corneal haze the subgroups were comparable. Success rates of trabeculotomy, trabeculectomy, and a combined procedure did not significantly differ when assessed by life table analysis. Patient age under 3 months (p = 0.014) and an ocular axial length of 24 mm or more (p = 0.016) proved to be major risk factors for primary ab externo surgery failure. A second operation was necessary in 20 of 61 eyes (32.8%) during follow up.
Prognosis of primary ab externo glaucoma surgery in primary congenital glaucoma seems to be governed more by the individual course and severity of the disease than by modification of surgical techniques.
在过去十年中,原发性先天性青光眼的减压手术策略发生了变化。外路滤过手术——例如小梁切除术或小梁切开术联合小梁切除术,现在甚至已被接受作为主要干预手段。
作者回顾了1988年至1996年间连续35例原发性先天性青光眼患者的61只眼睛,这些患者接受了不同类型的初始外路手术(中位随访时间36个月),以确定不同手术技术的疗效以及各种危险因素的影响。
17只眼睛(27.9%)进行了小梁切开术,15只眼睛(24.6%)进行了小梁切开术联合小梁切除术,29只眼睛(47.5%)进行了小梁切除术。在年龄、术前眼压、角膜直径、眼轴长度和角膜混浊发生率方面,各亚组具有可比性。通过生命表分析评估时,小梁切开术、小梁切除术和联合手术的成功率没有显著差异。3个月以下的患者年龄(p = 0.014)和24毫米或更长的眼轴长度(p = 0.016)被证明是原发性外路手术失败的主要危险因素。在随访期间,61只眼睛中有20只(32.8%)需要进行二次手术。
原发性先天性青光眼原发性外路青光眼手术的预后似乎更多地取决于疾病的个体病程和严重程度,而不是手术技术的改进。