Vick D J, Goodman Z D, Deavers M T, Cain J, Ishak K G
Department of Pathology and Area Laboratory Services, Walter Reed Army Medical Center, Washington, DC, USA.
Am J Surg Pathol. 1999 Jun;23(6):671-7. doi: 10.1097/00000478-199906000-00006.
Ciliated hepatic foregut cyst (CHFC) is a rare, benign, solitary cyst consisting of ciliated pseudostratified columnar epithelium, subepithelial connective tissue, a smooth muscle layer, and an outer fibrous capsule. We studied six previously unreported cases of CHFC and 50 cases from the literature. The literature search revealed that Friedreich first described the lesion in 1857 and hypothesized its congenital origin. The cyst generally is found incidentally on radiologic imaging or during surgical exploration, although one case presented with portal vein compression. It occurs more frequently in men and is found most commonly in the medial segment of the left hepatic lobe, unlike most other solitary cysts that show a female predominance and greater occurrence in the right hepatic lobe. Two of the 56 cases were multilocular. There has been an increase in the number of reports of CHFC during the past 15 years. This may reflect the increased availability and use of various radiologic imaging modalities. A large number of cases have been reported in the Japanese population, but the significance of this is unclear. CHFC should be considered in the differential diagnosis of other solitary liver cysts, including simple cysts, hepatobiliary cystadenomas, and parasitic cysts.
纤毛肝前肠囊肿（CHFC）是一种罕见的良性孤立性囊肿，由纤毛假复层柱状上皮、上皮下结缔组织、平滑肌层和外层纤维囊组成。我们研究了6例此前未报道的CHFC病例以及文献中的50例病例。文献检索显示，弗里德里希于1857年首次描述了该病变，并推测其为先天性起源。该囊肿通常在影像学检查或手术探查时偶然发现，尽管有1例表现为门静脉受压。它在男性中更常见，最常发生于左肝叶内侧段，这与大多数其他孤立性囊肿不同，后者女性居多且在右肝叶更常见。56例中有2例为多房性。在过去15年中，CHFC的报道数量有所增加。这可能反映了各种影像学检查手段的可及性和使用的增加。日本人群中有大量病例报道，但尚不清楚其意义。在鉴别诊断其他孤立性肝囊肿时，应考虑CHFC，包括单纯囊肿、肝胆管囊腺瘤和寄生虫性囊肿。
