Jakowski Joseph D, Lucas Joel G, Seth Sumit, Frankel Wendy L
Department of Pathology, The Ohio State University, Columbus, OH 43210, USA.
Ann Diagn Pathol. 2004 Dec;8(6):342-6. doi: 10.1053/j.anndiagpath.2004.08.004.
We report a case of a ciliated hepatic foregut cyst (CHFC) in the left lobe of the liver in a 42-year-old woman. To date, only 60 cases of these respiratory epithelial lined hepatic cysts have been reported since first described by Friedrich in 1857. CHFC are believed to be congenitally derived from the embryonic foregut and are considered benign lesions that are most often unilocular. Recently, however, there has been documented malignant transformation in these cysts. The majority of patients with a CHFC are asymptomatic and the cyst is usually an incidental finding during abdominal imaging studies or during surgical exploration. Interestingly, 85% of the total number of cases of CHFC have been reported within the last two decades. This recent rise in case reports is likely explained by greater detection because of the dramatic rise in the use of abdominal imaging. In our case, however, ultrasound failed to demonstrate any lesion within the liver and on computed tomography the cyst was more consistent with a soft tissue mass. Therefore, pathologic evaluation was necessary for the correct diagnosis of this liver lesion and to exclude malignancy.
我们报告一例42岁女性肝脏左叶的纤毛前肠囊肿(CHFC)。自1857年弗里德里希首次描述以来,迄今为止,仅有60例这种由呼吸道上皮衬里的肝囊肿的病例报告。CHFC被认为是先天性起源于胚胎前肠,被视为良性病变,大多为单房性。然而,最近已有这些囊肿发生恶性转化的记录。大多数CHFC患者无症状,囊肿通常是在腹部影像学检查或手术探查时偶然发现的。有趣的是,CHFC病例总数的85%是在过去二十年中报告的。近期病例报告的增加可能是由于腹部影像学检查使用的显著增加,从而提高了检出率。然而,在我们的病例中,超声未能显示肝脏内有任何病变,而在计算机断层扫描中,该囊肿更像是一个软组织肿块。因此,对该肝脏病变进行病理评估对于正确诊断并排除恶性肿瘤是必要的。