Lanzola E, Allegrini M, Roggi C, Montani A
S TA NU. 1976 Sep-Dec;6(5-6):277-80.
40 wistar rats were divided into two groups which had been fed one year earlier a diet in which 30% of the caloric intake consisted of rapeseed oil and peanut oil respectively. Both groups were then fed a diet of 30% peanut oil for five months and then fed a normal diet for seven months. At this time each of the two main groups was subdivided into four smaller groups, each group receiving a different diet: one of 25% rapeseed oil, one of 25% peanut oil, one of 25% butter, and one internal control group. At the end of the experiment the rats were sacrificed by decapitation. One portion of each heart was used for measuring its fatty acid content and the remaining portion was used for preparing sarcosomes on which the exigen consumption was measured polarographically. It was found that no erucic acid was present in the hearts of the rats fed rapeseed oil one year previously, and then then refed the same diet in the present experiment. The mitochondrial respiratory activity of the treated rats did not show any significant difference with respect to the found in the control groups, unlike the first experiment.
40只Wistar大鼠被分为两组，一年前分别喂食热量摄入30%由菜籽油和花生油组成的饮食。然后两组均喂食5个月含30%花生油的饮食，接着喂食7个月正常饮食。此时，两个主要组各自再细分为四个较小的组，每组接受不同饮食：一组含25%菜籽油，一组含25%花生油，一组含25%黄油，还有一个内部对照组。实验结束时，大鼠断头处死。每颗心脏的一部分用于测量其脂肪酸含量，其余部分用于制备肌粒，通过极谱法测量其上的耗氧量。结果发现，在本实验中，一年前喂食菜籽油且之后再次喂食相同饮食的大鼠心脏中不存在芥酸。与第一个实验不同，处理组大鼠的线粒体呼吸活性与对照组相比未显示出任何显著差异。
