Jiang C
Hydatidosis Research Laboratory, Lanzhou Medical College, China.
Chin Med J (Engl). 1998 May;111(5):470-5.
All reference data originated from related Chinese- or English-language literature in Chinese journals.
Twenty-three original articles published in 1992-1996 were selected according to the stated purpose and 9 of them were written by myself.
The present paper dealt with 5 subtopics, i.e. epidemiology, parasitology, pathology, diagnosis, treatment and prognosis.
Five hundred and eighty-four patients with alveolar echinococcosis (AE) have been reported from 7 provinces or autonomous regions. Human infection rate was 19.2% or 2.8%, and the morbidity was 2.4%-5.0%. The intermediate hosts of Echinococcus multilocularis included 7 species of rodents and 3 species of livestocks, and the final hosts of that were fox, dog or wolf. Diagnosis of AE was chiefly based on imaging examination (ultrasound and CT) and immunological test. The operative resection rate for liver AE was only 10.5% (27/258). Albendazole was a certain remedy for the chemotherapy of AE, and TCM "Xiao-Bao" pill may be a hopeful drug.
In the past 30 years, a lot of work concerning basic and clinical studies has been done in China and some achievements have been achieved. However, some important problems such as how to conduct further research on molecular biology, how to make early diagnosis, how to improve the chemotherapeutic effect, and how to control the prevalence of AE, need to be studied more deeply in the 21st century.
所有参考文献数据均源自中国期刊上的相关中英文文献。
根据既定目的选取了1992 - 1996年发表的23篇原创文章，其中9篇为本人撰写。
本文涉及5个主题，即流行病学、寄生虫学、病理学、诊断、治疗与预后。
7个省或自治区共报告了584例肺泡型棘球蚴病（AE）患者。人群感染率为19.2%或2.8%，发病率为2.4% - 5.0%。多房棘球绦虫的中间宿主包括7种啮齿动物和3种家畜，终末宿主为狐狸、狗或狼。AE的诊断主要基于影像学检查（超声和CT）及免疫学检测。肝AE的手术切除率仅为10.5%（27/258）。阿苯达唑是AE化疗的一种有效药物，中药“消包”丸可能是一种有希望的药物。
在过去30年里，中国在基础和临床研究方面做了大量工作并取得了一些成果。然而，一些重要问题，如如何在分子生物学方面开展进一步研究、如何进行早期诊断、如何提高化疗效果以及如何控制AE的流行，在21世纪仍需更深入地研究。
