Walsh C H, Baylis P H, Malins J M
Diabetologia. 1979 Feb;16(2):93-6. doi: 10.1007/BF01225456.
Plasma Arginine Vasopressin (AVP) was measured serially in 10 patients during the first 24 hours of treatment of diabetic ketoacidosis. AVP was elevated in all cases initially, ranging from 4.0--122.0 pmol/l, the basal level in healthy hydrated subjects being 1.57 +/- 0.59 pmol/l (+/- 1 SD). The levels fell progressively during the course of treatment. While there was no evidence that the massive increases in AVP noted in this study were associated with water overload it remains to be determined whether the high levels observed have any significant metabolic or haemodynamic role in this disorder.
在10例糖尿病酮症酸中毒患者治疗的最初24小时内，对其血浆精氨酸加压素（AVP）进行了连续测定。所有病例最初AVP均升高，范围为4.0--122.0 pmol/l，健康水合受试者的基础水平为1.57±0.59 pmol/l（±1标准差）。在治疗过程中，其水平逐渐下降。虽然没有证据表明本研究中观察到的AVP大量增加与水负荷过多有关，但尚有待确定所观察到的高水平在该疾病中是否具有任何显著的代谢或血流动力学作用。
