Deichmann M, Thome M, Bock M, Jäckel A, Waldmann V, Näher H
Universitäts-Hautklinik Heidelberg, Germany.
Br J Cancer. 1999 Apr;80(1-2):67-9. doi: 10.1038/sj.bjc.6690322.
Malignant melanomas were supposed to harbour the human herpesvirus-type 8 (HHV-8) genome, as melanoma cells were reported to express interleukin-6 and a homologue of interleukin-6 was found in the HHV-8 genome. We therefore investigated 33 primary malignant melanomas by polymerase chain reaction, but could not find this tumorigenic gamma-herpesvirus in any tumour.
恶性黑色素瘤被认为携带着人类8型疱疹病毒(HHV - 8)基因组,因为据报道黑色素瘤细胞可表达白细胞介素 - 6,并且在HHV - 8基因组中发现了白细胞介素 - 6的一个同源物。因此,我们通过聚合酶链反应对33例原发性恶性黑色素瘤进行了研究,但在任何肿瘤中均未发现这种致瘤性γ疱疹病毒。