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经皮胆囊造瘘术在高危手术患者中的有效应用:技术、导管管理及结果

Effective use of percutaneous cholecystostomy in high-risk surgical patients: techniques, tube management, and results.

作者信息

Davis C A, Landercasper J, Gundersen L H, Lambert P J

机构信息

Department of Surgery, Gundersen Lutheran Medical Center, La Crosse, Wis. 54601, USA.

出版信息

Arch Surg. 1999 Jul;134(7):727-31; discussion 731-2. doi: 10.1001/archsurg.134.7.727.

Abstract

HYPOTHESIS

Percutaneous cholecystostomy (PC) is an effective, safe treatment in patients with suspected acute cholecystitis and severe concomitant comorbidity.

DESIGN

Retrospective medical record review from March 1989 to March 1998.

SETTING

Referral community teaching hospital (450 beds) in rural Wisconsin.

PATIENTS

Twenty-two consecutive patients underwent PC tube placement over a 10-year period. Twenty procedures were for acute cholecystitis (14 calculous, 6 acalculous) and 2 were for diagnostic dilemmas. Nineteen (86%) of 22 patients were American Society of Anesthesiologists class 4; 3 (14%) were class 3.

INTERVENTIONS

Pigtail catheters (8F-10F) placed by means of ultrasound or computed tomographic localization, with or without fluoroscopic adjunct.

MAIN OUTCOME MEASURES

Thirty-day mortality, complications, clinical improvement as determined by fever and pain resolution, normalization of leukocytosis, further biliary procedures required, and outcome after drain removal.

RESULTS

Twenty-two patients underwent PC for presumed acute cholecystitis based on ultrasound and clinical findings. All patients received antibiotics prior to PC for 24 or more hours. Thirty-day mortality was 36% (8 patients), reflecting severity of concomitant disease. Minor complications occurred in 3 of 22 patients. Clinical improvement occurred in 18 (82%) of 22 patients-15 (68%) within 48 hours. Follow-up of fourteen 30-day survivors is as follows: 7 (50%) had drains removed because the gallbladder was stone free, 4 (29%) had drains remaining due to persistent stones, 2 (14%) underwent cholecystectomy, and 1 (7%) awaits scheduled surgery. Only 1 (12.5%) of 8 patients developed biliary complications after drain removal, requiring endoscopic retrograde cholangiopancreatography 9 months after drain removal. One patient required urgent cholecystectomy after failure to respond to PC. This patient died of a perioperative myocardial infarction.

CONCLUSIONS

Percutaneous cholecystostomy is an effective, safe treatment in patients with suspected acute cholecystitis and severe concomitant comorbidity. Laparoscopic cholecystectomy is recommended as definitive treatment for patients whose risk for general anesthesia improves in follow-up. Drains can be safely removed once all gallstones are cleared. In patients with severe concomitant disease, drains can be left with a low incidence of complications if stones remain.

摘要

假设

经皮胆囊造瘘术(PC)对于疑似急性胆囊炎并伴有严重合并症的患者是一种有效且安全的治疗方法。

设计

回顾性病历研究,时间跨度为1989年3月至1998年3月。

地点

威斯康星州农村的一所转诊社区教学医院(450张床位)。

患者

在10年期间,连续22例患者接受了PC管置入术。其中20例为急性胆囊炎(14例有结石,6例无结石),2例用于解决诊断难题。22例患者中有19例(86%)为美国麻醉医师协会4级;3例(14%)为3级。

干预措施

通过超声或计算机断层扫描定位置入猪尾导管(8F - 10F),可辅以或不辅以荧光透视。

主要观察指标

30天死亡率、并发症、根据发热和疼痛缓解情况、白细胞增多症恢复正常、是否需要进一步的胆道手术以及拔管后的结局来判定临床改善情况。

结果

22例患者基于超声和临床检查结果因疑似急性胆囊炎接受了PC治疗。所有患者在PC术前均接受了24小时或更长时间的抗生素治疗。30天死亡率为36%(8例患者),反映了合并症的严重程度。22例患者中有3例出现轻微并发症。22例患者中有18例(82%)出现临床改善,其中15例(68%)在48小时内改善。对14例30天存活患者的随访情况如下:7例(50%)因胆囊无结石而拔除引流管,4例(29%)因结石持续存在而保留引流管,2例(14%)接受了胆囊切除术,1例(7%)等待 scheduled 手术。8例患者中只有1例(12.5%)在拔管后出现胆道并发症,在拔管9个月后需要进行内镜逆行胰胆管造影术。1例患者在PC治疗无效后需要紧急胆囊切除术。该患者死于围手术期心肌梗死。

结论

经皮胆囊造瘘术对于疑似急性胆囊炎并伴有严重合并症的患者是一种有效且安全的治疗方法。对于全身麻醉风险在随访中有所改善的患者,建议行腹腔镜胆囊切除术作为确定性治疗。一旦所有胆结石清除,引流管可安全拔除。对于伴有严重合并症的患者,如果结石仍然存在,保留引流管的并发症发生率较低。

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