Uutela K, Hämäläinen M, Somersalo E
Brain Research Unit, Low Temperature Laboratory, Espoo, FIN-02015 HUT, Finland.
Neuroimage. 1999 Aug;10(2):173-80. doi: 10.1006/nimg.1999.0454.
The locations of active brain areas can be estimated from the magnetic field the neural current sources produce. In this work we study a visualization method of magnetoencephalographic data that is based on minimum[symbol: see text] (1)-norm estimates. The method can represent several local or distributed sources and does not need explicit a priori information. We evaluated the performance of the method using simulation studies. In a situation resembling typical magnetoencephalographic measurement, the mean estimated source strength exceeded baseline level up to 2 cm from the simulated point-like source. The method can also visualize several sources, activated simultaneously or in a sequence, which we demonstrated by analyzing magnetic responses associated with sensory stimulation and a picture naming task.
活跃脑区的位置可根据神经电流源产生的磁场来估计。在这项工作中,我们研究了一种基于最小[符号:见原文](1)-范数估计的脑磁图数据可视化方法。该方法可以表示多个局部或分布式源,并且不需要明确的先验信息。我们通过模拟研究评估了该方法的性能。在类似于典型脑磁图测量的情况下,平均估计源强度在距模拟点状源2厘米处超过基线水平。该方法还可以可视化同时或按顺序激活的多个源,我们通过分析与感觉刺激和图片命名任务相关的磁响应来证明这一点。