Hashim I A, Zawawi T H
Department of Pathology, King Khalid National Guard Hospital, Jeddah, Saudi Arabia.
Ir J Med Sci. 1999 Apr-Jun;168(2):114-8. doi: 10.1007/BF02946479.
Analysis of renal stones may help in elucidating the pathogenesis of nephro-lithiasis. This study compared the use of 2 methods for the analysis of renal stones. One method is qualitative dry 'spot tests' whereas the other is quantitative 'wet chemistry.' In the wet chemistry method, dissolved stone material were analysed using automated chemistry analysers, whereas, the dry method involved spot colour end-point detection. Stones (n = 64) were analysed by both methods. The majority of stones were calcium oxalate as determined by wet chemistry (57.4 per cent) and spot tests (50.0 per cent). Fewer mixed stones were obtained by the wet chemistry method (16.8 per cent) compared with the spot tests method (39.0 per cent), whereas, more uric acid stones were obtained by the wet chemistry method (5.6 per cent) compared with the spot tests method (1.9 per cent). 'Pure' calcium phosphate stones (3.0 per cent) were only obtained by the wet chemistry method. In the wet chemistry method, dissolved stone material did not show significant deterioration on storage for up to 9 days.
肾结石分析有助于阐明肾结石的发病机制。本研究比较了两种肾结石分析方法的使用情况。一种方法是定性干“斑点试验”，另一种是定量“湿化学法”。在湿化学法中，使用自动化学分析仪分析溶解的结石物质，而干法涉及斑点颜色终点检测。两种方法都对64颗结石进行了分析。通过湿化学法（57.4%）和斑点试验（50.0%）确定，大多数结石为草酸钙结石。与斑点试验法（39.0%）相比，湿化学法获得的混合结石较少（16.8%），而与斑点试验法（1.9%）相比，湿化学法获得的尿酸结石较多（5.6%）。“纯”磷酸钙结石（3.0%）仅通过湿化学法获得。在湿化学法中，溶解的结石物质在储存长达9天的时间内未显示出明显变质。
