Jiang B, Lu Z Q, Hou A J, Zhao Q S, Sun H D
Laboratory of Phytochemistry, Kunming Institute of Botany, Academia Sinica, Kunming, 650204, Yunnan, China.
J Nat Prod. 1999 Jul;62(7):941-5. doi: 10.1021/np980426f.
Six new ent-kaurane diterpenoids, lungshengenins B-G (1-6), together with three known diterpenoids, lungshengenin A (7), inflexin (8), and lushanrubescinsin C (9), were isolated from the leaves and tender branches of Isodon lungshengensis. Their structures were elucidated by means of spectroscopy, mainly 1D and 2D NMR techniques. Lungshengenins A (7), C (2), and G (6) were cytotoxic toward K562 cells, having IC(50) values equal to or less than 10 microg/mL.
从线纹香茶菜的叶和嫩枝中分离得到6个新的对映-贝壳杉烷二萜，龙神皂苷元B-G（1-6），以及3个已知二萜，龙神皂苷元A（7）、弯曲菌素（8）和庐山香茶菜辛素C（9）。通过光谱学方法，主要是一维和二维核磁共振技术对它们的结构进行了阐明。龙神皂苷元A（7）、C（2）和G（6）对K562细胞具有细胞毒性，半数抑制浓度（IC50）值等于或小于10微克/毫升。
