DiBartolomeo J R
West J Med. 1976 Jan;124(1):13-7.
Scleroma of the respiratory tract was first recognized just over a century ago. The disease is endemic in a number of North African, Central American and Latin American countries. However, it has been only rarely seen in the United States. The progression of scleroma takes place through three stages. The first stage of rhinitis has an early catarrhal phase which progresses to one of atrophic rhinitis. The second stage is seen as a proliferative granulomatous growth which obliterates the nasal fossae. The third cicatricial stage is usually accompanied by pronounced scarring and retraction of the tissues involved. Because of the increased ease of international travel by both sea and air, more cases can be expected to occur in the United States. This paper is presented to alert physicians to suspect scleroma in any case of granulomatous disease of the respiratory tract.
呼吸道硬结病于一个多世纪前首次被发现。该疾病在一些北非、中美洲和拉丁美洲国家呈地方性流行。然而，在美国却很少见。硬结病的发展过程分为三个阶段。第一阶段为鼻炎，初期有卡他期，随后发展为萎缩性鼻炎。第二阶段表现为增殖性肉芽肿生长，可使鼻窝闭塞。第三阶段为瘢痕期，通常伴有受累组织明显的瘢痕形成和收缩。由于通过海路和航空进行国际旅行越来越便捷，预计美国会出现更多病例。本文旨在提醒医生，对于任何呼吸道肉芽肿性疾病病例，都要怀疑硬结病。
