Goren A I, Hellman S, Brenner S, Egoz N, Rishpon S
Research Institute for Environmental Health, Tel Aviv University Sackler School of Medicine, Israel.
Environ Health Perspect. 1990 Nov;89:225-31. doi: 10.1289/ehp.9089225.
During spring 1984, 2334 second and 2000 fifth-grade schoolchildren living in three Haifa Bay areas on the eastern Mediterranean coast with different levels of air pollution were studied. The parents of these children filled out American Thoracic Society and National Heart and Lung Institute health questionnaires, and the children performed the following pulmonary function tests (PFT); FVC, FEV1, FEV1/FEV, PEF, FEF50, and FEF75. A trend of higher prevalence of most reported respiratory symptoms was found for schoolchildren growing up in the medium and high pollution areas as compared with the low pollution area. Part of the reported respiratory diseases were significantly more common among children from the high pollution area. Models fitted for the respiratory conditions that differed significantly among the three areas of residence also included background variables that could be responsible for these differences. Relative risk values, which were calculated from the logistic models, were in the range of 1.38 for sputum with cold and 1.81 for sputum without cold for children from the high pollution area as compared with 1.00 for children from the low pollution area. All the measured values of PFT were within the normal range. There was no consistent trend of reduced pulmonary function that characterized any residential area.
1984年春季,对居住在地中海东部海岸海法湾三个空气污染程度不同地区的2334名二年级和2000名五年级学童进行了研究。这些孩子的父母填写了美国胸科学会和国家心肺研究所的健康调查问卷,孩子们进行了以下肺功能测试(PFT):用力肺活量(FVC)、第一秒用力呼气量(FEV1)、FEV1/FVC、呼气峰值流速(PEF)、50%用力呼气流量(FEF50)和75%用力呼气流量(FEF75)。结果发现,与低污染地区相比,在中度和高度污染地区长大的学童报告的大多数呼吸道症状患病率呈上升趋势。报告的部分呼吸道疾病在高污染地区的儿童中明显更为常见。针对三个居住地区之间存在显著差异的呼吸道疾病所拟合的模型还包括可能导致这些差异的背景变量。根据逻辑模型计算的相对风险值,高污染地区儿童感冒时咳痰的相对风险值为1.38,不感冒时咳痰的相对风险值为1.81,而低污染地区儿童的相对风险值为1.00。所有肺功能测试的测量值均在正常范围内。没有一致的趋势表明任何居住地区的肺功能下降。