来自硬叶法贡的三萜皂苷。

Triterpenoid saponins from Fagonia indica.

作者信息

Shaker K H, Bernhardt M, Elgamal M H, Seifert K

机构信息

University of Bayreuth, Germany.

出版信息

Phytochemistry. 1999 Aug;51(8):1049-53. doi: 10.1016/s0031-9422(98)00750-x.

DOI:10.1016/s0031-9422(98)00750-x

PMID:10444859

Abstract

Two new triterpenoid saponins, 3-O-{[beta-D-glucopyranosyl-(1-->2)]-[alpha-L-arabinopyranosyl-(1- ->3)]- alpha-L-arabinopyranosyl}-ursolic acid-28-O-[beta-D-glucopyranosyl] ester (indicasaponin A), 3-O-{[beta-D-glucopyranosyl-(1-->2)]-[alpha-L-arabinopyranosyl-(1- ->3)]- alpha-L-arabinopyranosyl}-oleanolic acid-28-O-[beta-D-glucopyranosyl] ester (indicasaponin B) and two known triterpenoid saponins, 3-O-[beta-D-glucopyranosyl-(1-->3)-alpha-L-arabinopyranosyl]-ur solic acid-28-O-[beta-D-glucopyranosyl] ester, 3-O-[beta-D-glucopyranosyl-(1-->3)-alpha-L-arabinopyranosyl]-olean olic acid-28-O-[beta-D-glucopyranosyl] ester have been isolated from Fagonia indica. The structures were determined primarily by NMR spectroscopy. The assignment of NMR signals was performed by means of 1H-1H COSY, NOESY, ROESY, TOCSY, HMQC and HMBC experiments.

摘要

从刺山柑中分离出两种新的三萜皂苷，3-O-{[β-D-吡喃葡萄糖基-(1→2)]-[α-L-吡喃阿拉伯糖基-(1→3)]-α-L-吡喃阿拉伯糖基}-乌索酸-28-O-[β-D-吡喃葡萄糖基]酯（刺山柑皂苷A）、3-O-{[β-D-吡喃葡萄糖基-(1→2)]-[α-L-吡喃阿拉伯糖基-(1→3)]-α-L-吡喃阿拉伯糖基}-齐墩果酸-28-O-[β-D-吡喃葡萄糖基]酯（刺山柑皂苷B）以及两种已知的三萜皂苷，3-O-[β-D-吡喃葡萄糖基-(1→3)-α-L-吡喃阿拉伯糖基]-乌索酸-28-O-[β-D-吡喃葡萄糖基]酯、3-O-[β-D-吡喃葡萄糖基-(1→3)-α-L-吡喃阿拉伯糖基]-齐墩果酸-28-O-[β-D-吡喃葡萄糖基]酯。其结构主要通过核磁共振光谱法确定。核磁共振信号的归属通过1H-1H COSY、NOESY、ROESY、TOCSY、HMQC和HMBC实验完成。