Darchy B, Abruzzese L, Pitiot O, Figueredo B, Domart Y
Service de Réanimation Médico-chirurgicale, Centre Hospitalier, 8, avenue Henri Adnot, 60 200 Compiègne, France.
Intensive Care Med. 1999 Aug;25(8):859-61. doi: 10.1007/s001340050966.
In the absence of an immediately available serum ethylene glycol (EG) assay, the diagnosis of EG poisoning is usually based on anamnesis, clinical findings and presence of metabolic acidosis with elevated serum anion gap, elevated serum osmol gap, hypocalcemia and crystalluria. We report two cases of EG poisoning, both presenting without an elevated serum osmol gap and we discuss conditions which facilitate such a presentation, especially delayed hospital admission. Finally, we confirm the fact that determination of the osmol gap can fail as a screen for EG poisoning.
在无法立即进行血清乙二醇（EG）检测的情况下，EG中毒的诊断通常基于病史、临床表现以及存在代谢性酸中毒伴血清阴离子间隙升高、血清渗透压间隙升高、低钙血症和结晶尿。我们报告了两例EG中毒病例，这两例均无血清渗透压间隙升高的表现，并且我们讨论了促使出现这种表现的情况，尤其是延迟入院。最后，我们证实了渗透压间隙测定作为EG中毒筛查手段可能失败这一事实。
