Grefer J, Santer R, Ankermann T, Faul S, Nölle B, Eggert P
Klinikum der Christian-Albrechts-Universität, Klinik für Allgemeine Pädiatrie, Kiel, Germany.
Pediatr Nephrol. 1999 May;13(4):336-9. doi: 10.1007/s004670050621.
The case of a 13.5-year-old girl with acute tubulointerstitial nephritis and uveitis (TINU syndrome) is presented. The etiology of this rare syndrome, which in most cases involves female adolescents and usually regresses spontaneously, is still unknown. An infection-triggered pathological immune reaction has been considered to play a role in the pathogenesis of this disorder. Here we report for the first time the association of TINU syndrome and Epstein-Barr virus infection.
本文报告了一例13.5岁患急性肾小管间质性肾炎和葡萄膜炎(TINU综合征)的女孩。这种罕见综合征的病因尚不清楚,大多数病例发生在女性青少年中,通常会自发缓解。一种由感染引发的病理性免疫反应被认为在该疾病的发病机制中起作用。在此,我们首次报告了TINU综合征与爱泼斯坦-巴尔病毒感染之间的关联。