Self-Assembly of a Tetrahedral Lectin into Predesigned Diamondlike Protein Crystals.

作者信息

Dotan N, Arad D, Frolow F, Freeman A

机构信息

Department of Molecular Microbiology and Biotechnology, Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978 (Israel).

出版信息

Angew Chem Int Ed Engl. 1999 Aug;38(16):2363-2366.

PMID:10458787

Abstract

Binding sites analogous to those of sp(3) carbon are presented by concanavalin A. This lectin has now been cross-linked with a bismannopyranoside which contains the C(2) spacer required to form the computer-modeled diamondlike three-dimensional protein lattice shown in the picture.

摘要