Liu J M, Lin W C, Chen Y M, Wu H W, Yao N S, Chen L T, Whang-Peng J
National Health Research Institutes, Veterans General Hospital, Taipei, Taiwan, Republic of China.
J Med Ethics. 1999 Aug;25(4):309-14. doi: 10.1136/jme.25.4.309.
To report and analyse the pattern of end-of-life decision making for terminal Chinese cancer patients.
Retrospective descriptive study.
A cancer clinical trials unit in a large teaching hospital.
From April 1992 to August 1997, 177 consecutive deaths of cancer clinical trial patients were studied.
Basic demographic data, patient status at the time of signing a DNR consent, or at the moment of returning home to die are documented, and circumstances surrounding these events evaluated.
DNR orders were written for 64.4% of patients. Patients in pain (odds ratio 0.45, 95% CI 0.22-0.89), especially if requiring opioid analgesia (odds ratio 0.40, 95% CI 0.21-0.77), were factors associated with a higher probability of such an order. Thirty-five patients were taken home to die, a more likely occurrence if the patient was over 75 years (odds ratio 0.12, 95% CI 0.04-0.34), had children (odds ratio 0.14, 95% CI 0.02-0.79), had Taiwanese as a first language (odds ratio 6.74, 95% CI 3.04-14.93), or was unable to intake orally (odds ratio 2.73, 95% CI 1.26-5.92). CPR was performed in 30 patients, none survived to discharge.
DNR orders are instituted in a large proportion of dying Chinese cancer patients in a cancer centre, however, the order is seldom signed by the patient personally. This study also illustrates that as many as 20% of dying patients are taken home to die, in accordance with local custom.
报告并分析晚期中国癌症患者的临终决策模式。
回顾性描述性研究。
一家大型教学医院的癌症临床试验单位。
对1992年4月至1997年8月期间癌症临床试验患者连续177例死亡病例进行研究。
记录基本人口统计学数据、签署“不进行心肺复苏”(DNR)同意书时或回家等死时的患者状况,并评估这些事件的相关情况。
64.4%的患者下达了DNR医嘱。处于疼痛中的患者(优势比0.45,95%置信区间0.22 - 0.89),尤其是需要阿片类镇痛剂的患者(优势比0.40,95%置信区间0.21 - 0.77),是下达此类医嘱可能性较高的相关因素。35例患者被送回家等死,如果患者年龄超过75岁(优势比0.12,95%置信区间0.04 - 0.34)、有子女(优势比0.14,95%置信区间0.02 - 0.79)、母语为台湾话(优势比6.74,95%置信区间3.04 - 14.93)或无法经口进食(优势比2.73,95%置信区间1.26 - 5.92),则更有可能出现这种情况。30例患者接受了心肺复苏,但无一存活出院。
在癌症中心,很大一部分临终中国癌症患者下达了DNR医嘱,然而,该医嘱很少由患者本人签署。本研究还表明,多达20%的临终患者会按照当地习俗被送回家等死。