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癌症中心中国临床试验患者的“不要复苏”医嘱状况

The status of the do-not-resuscitate order in Chinese clinical trial patients in a cancer centre.

作者信息

Liu J M, Lin W C, Chen Y M, Wu H W, Yao N S, Chen L T, Whang-Peng J

机构信息

National Health Research Institutes, Veterans General Hospital, Taipei, Taiwan, Republic of China.

出版信息

J Med Ethics. 1999 Aug;25(4):309-14. doi: 10.1136/jme.25.4.309.

Abstract

OBJECTIVE

To report and analyse the pattern of end-of-life decision making for terminal Chinese cancer patients.

DESIGN

Retrospective descriptive study.

SETTING

A cancer clinical trials unit in a large teaching hospital.

PATIENTS

From April 1992 to August 1997, 177 consecutive deaths of cancer clinical trial patients were studied.

MAIN MEASUREMENT

Basic demographic data, patient status at the time of signing a DNR consent, or at the moment of returning home to die are documented, and circumstances surrounding these events evaluated.

RESULTS

DNR orders were written for 64.4% of patients. Patients in pain (odds ratio 0.45, 95% CI 0.22-0.89), especially if requiring opioid analgesia (odds ratio 0.40, 95% CI 0.21-0.77), were factors associated with a higher probability of such an order. Thirty-five patients were taken home to die, a more likely occurrence if the patient was over 75 years (odds ratio 0.12, 95% CI 0.04-0.34), had children (odds ratio 0.14, 95% CI 0.02-0.79), had Taiwanese as a first language (odds ratio 6.74, 95% CI 3.04-14.93), or was unable to intake orally (odds ratio 2.73, 95% CI 1.26-5.92). CPR was performed in 30 patients, none survived to discharge.

CONCLUSIONS

DNR orders are instituted in a large proportion of dying Chinese cancer patients in a cancer centre, however, the order is seldom signed by the patient personally. This study also illustrates that as many as 20% of dying patients are taken home to die, in accordance with local custom.

摘要

目的

报告并分析晚期中国癌症患者的临终决策模式。

设计

回顾性描述性研究。

地点

一家大型教学医院的癌症临床试验单位。

患者

对1992年4月至1997年8月期间癌症临床试验患者连续177例死亡病例进行研究。

主要测量指标

记录基本人口统计学数据、签署“不进行心肺复苏”(DNR)同意书时或回家等死时的患者状况,并评估这些事件的相关情况。

结果

64.4%的患者下达了DNR医嘱。处于疼痛中的患者(优势比0.45,95%置信区间0.22 - 0.89),尤其是需要阿片类镇痛剂的患者(优势比0.40,95%置信区间0.21 - 0.77),是下达此类医嘱可能性较高的相关因素。35例患者被送回家等死,如果患者年龄超过75岁(优势比0.12,95%置信区间0.04 - 0.34)、有子女(优势比0.14,95%置信区间0.02 - 0.79)、母语为台湾话(优势比6.74,95%置信区间3.04 - 14.93)或无法经口进食(优势比2.73,95%置信区间1.26 - 5.92),则更有可能出现这种情况。30例患者接受了心肺复苏,但无一存活出院。

结论

在癌症中心,很大一部分临终中国癌症患者下达了DNR医嘱,然而,该医嘱很少由患者本人签署。本研究还表明,多达20%的临终患者会按照当地习俗被送回家等死。

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Do-not-resuscitate orders--should the patient be informed?“不要复苏”医嘱——是否应告知患者?
J Intern Med. 1997 May;241(5):421-5. doi: 10.1046/j.1365-2796.1997.138144000.x.

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