狂犬病疫苗。采用分子生物学方法的进展。
Rabies vaccine. Developments employing molecular biology methods.
作者信息
Paolazzi C C, Pérez O, De Filippo J
机构信息
Servicio Vacuna Antirrábica, Instituto Nacional de Producción de Biológicos, A.N.L.I.S., Buenos Aires, Argentina.
出版信息
Mol Biotechnol. 1999 Apr;11(2):137-47. doi: 10.1007/BF02915807.
PMID:10464768
Abstract
Rabies vaccines produced by means of molecular biology are described. Recombinant vaccines employing either viruses as vectors (vaccinia, adenovirus, poxvirus, baculovirus, plant viruses) or a plasmid vector carrying the rabies virus glycoprotein gene are discussed. Synthetic peptide technology directed to rabies vaccine production is also presented.
摘要
描述了通过分子生物学方法生产的狂犬病疫苗。讨论了使用病毒作为载体（痘苗病毒、腺病毒、痘病毒、杆状病毒、植物病毒）或携带狂犬病病毒糖蛋白基因的质粒载体的重组疫苗。还介绍了用于狂犬病疫苗生产的合成肽技术。
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