位置，位置，还是位置：记忆形成的众多场所
Location, location, location: the many addresses of memory formation.
作者信息
Yin J C
机构信息
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
出版信息
Proc Natl Acad Sci U S A. 1999 Aug 31;96(18):9985-6. doi: 10.1073/pnas.96.18.9985.
Abstract
Memory formation, like real estate, can be summarized succinctly-location, location, location. It is an emergent property involving different anatomical regions in the brain, sets of neuronal circuits, and cellular and molecular interactions between and within those neurons. At each of these levels of description, location continues to be a major organizing principle guiding researchers. The difficulty in the field is the integration of information between the various levels of analyses, and it is proposed that molecular reporters may help to fill that void.
摘要
记忆形成，如同房地产一样，可以简洁地概括为——位置、位置、还是位置。它是一种涌现属性，涉及大脑中的不同解剖区域、神经元回路集合以及这些神经元之间和内部的细胞与分子相互作用。在这些描述层面的每一个层面上，位置仍然是指导研究人员的主要组织原则。该领域的困难在于整合不同分析层面之间的信息，并且有人提出分子报告基因可能有助于填补这一空白。
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