Ross B S, Levine V J, Nehal K, Tse Y, Ashinoff R
Department of Dermatology, Beth Israel Medical Center, New York, USA.
Dermatol Surg. 1999 May;25(5):377-80. doi: 10.1046/j.1524-4725.1999.07165.x.
Warts are a therapeutic challenge. New studies indicate that pulsed dye laser therapy may be effective, with clearance rates of 72 to 93%.
To determine clearance rate in pulsed dye laser treatment of warts and compare our rate to those of other published studies.
Thirty-three patients with 96 warts received pulsed dye laser treatment for recalcitrant plantar, digital, peri- and subungual, and body warts.
Forty-eight percent of patients had complete wart clearance; 45% partially cleared. Sixty-nine percent of those who cleared remained wart-free for an average of 11 months. Mean fluence was 9.4 J/cm2, with an average of 3.4 treatments. Body and palmar warts responded best, digital and peri- and subungual next, and plantar lesions worst. No significant side effects were observed.
Pulsed dye laser is an effective treatment option for recalcitrant warts with an excellent side effect profile. However, our response rates were not as high as those previously reported, and we feel that further studies would be useful.
疣是一种治疗难题。新研究表明,脉冲染料激光治疗可能有效,清除率为72%至93%。
确定脉冲染料激光治疗疣的清除率,并将我们的清除率与其他已发表研究的清除率进行比较。
33例患者共96个疣接受了脉冲染料激光治疗,这些疣包括顽固性跖疣、指疣、甲周及甲下疣和体疣。
48%的患者疣完全清除;45%部分清除。清除者中有69%平均11个月未再出现疣。平均能量密度为9.4 J/cm²,平均治疗3.4次。体疣和掌疣反应最佳,指疣、甲周及甲下疣次之,跖疣最差。未观察到明显副作用。
脉冲染料激光是治疗顽固性疣的一种有效选择,副作用极小。然而,我们的有效率不如先前报道的高,我们认为进一步研究将很有必要。